Our goal is to understand neural circuits underlying emotional behaviors and how they are perturbed in neuropsychiatric disease.
To this end we employ a combination of molecular, optogenetic, electrophysiological, and behavioral approaches.
We are identifying molecular biomarkers for psychiatric disease and using them to develop novel therapeutic approaches.
We have extensive experience with a variety of optical techniques including fiber photometry and optogenetics, which allow us to study the endogenous and causal dynamics of genetically specified cells and circuits in vivo.
We employ a variety of behavioral tests designed to assess motivated behaviors relevant to psychiatric disease, which give us a functional readout of our molecular and circuit manipulations.